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IĆ22 800 Series Operator's Manual
Hyperlipemia can result in artificially increased methemoglobin
values.
42,
43
High bilirubin concentrations can falsely increase oxyhemoglobin
values. Hyperlipemia and administration of fat emulsions can increase total
hemoglobin values. Samples frozen with liquid nitrogen can have decreased total
hemoglobin levels.
43
Samples from patients receiving blood substitutes yield
unreliable results for oxygen content blood due to the different oxygen solubility of
the blood substitutes.
Total Hemoglobin
Total hemoglobin (tHb) is the total of all measured hemoglobin fractions.
38
Total
hemoglobin determination is important in the assessment of oxygen transport and
in the evaluation of anemia. The total hemoglobin reference range for a normal
adult population is 12.0 to 18.0 g/dL.
Total hemoglobin in the CO-ox module is determined using the following
equation:
tHb = FO
2
Hb + FHHb + FMetHb + FCOHb
Oxyhemoglobin
Oxyhemoglobin (O
2
Hb) is the fraction of hemoglobin that is reversibly bound to
oxygen.
38
The oxyhemoglobin reference range for arterial blood for a normal
population is 94.0 to 97.0%.
The percent of oxyhemoglobin is determined using the following equation:
FO
2
Hb +
cO
2
Hb
ctHb
100
Deoxyhemoglobin
Deoxyhemoglobin (HHb) refers to the hemoglobin capable of binding oxygen.
Deoxyhemoglobin is sometimes referred to as reduced hemoglobin.
38
The
deoxyhemoglobin reference range for arterial blood for a normal population is 0.0
to 5.0%.
The percent of deoxyhemoglobin is determined using the following equation:
FHHb +
cHHb
ctHb
100